A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
Count Alucard (Lon Chaney Jr.) travels to a castle in Hungary seeking a cure for his vampirism, which he believes is linked to his werewolf curse. He finds Dr. Edelmann (Onslow Stevens), a scientist who has been experimenting with rejuvenation. Alucard inadvertently brings Dracula (John Carradine) back from the dead, and together they begin to plague the local villagers. As Edelmann tries to find a way to destroy them, he becomes entangled in their dark world.
House of Dracula was a product of Universal Pictures' declining monster movie cycle. While it attempted to tie together multiple Universal horror franchises, it was generally seen as less effective than its predecessors, with critics noting a formulaic plot and less compelling performances. Audiences at the time, however, were still drawn to the established monsters.
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This film is notable for being the only time Lon Chaney Jr. played the character of Count Alucard (Dracula spelled backward) and for featuring the Frankenstein monster's brain, though the monster itself does not appear.
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